Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia

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Cardio-ankle vascular index in heterozygous familial hypercholesterolemia.

AIM The cardio-ankle vascular index (CAVI) is a new non-invasive marker of arterial stiffness and atherosclerosis. The purpose of this study was to compare CAVI in patients with heterozygous familial hypercholesterolemia (FH) and in healthy controls. METHODS 82 FH subjects (27 males, 65 females), aged 53.7±13.6 years without clinical symptoms of cardiovascular diseases and 359 healthy control...

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Heterozygous Familial Hypercholesterolemia.

Familial hypercholesterolemia (FH) is a genetic condition that causes high low-density lipoprotein (LDL) cholesterol (sometimes referred to as bad cholesterol) from birth. FH means high cholesterol that runs in a family. FH is caused by specific DNA changes that are passed on from parents to their children. It is not caused by lifestyle factors such as a high-fat diet or lack of exercise. There...

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Effect of nitroglycerin administration on cardio-ankle vascular index

PURPOSE The purpose of this study was to clarify the difference between effects of nitroglycerin (NTG) on the functional stiffness in patients with and without coronary artery disease (CAD) using a newly developed stiffness index, cardio-ankle vascular index (CAVI). SUBJECTS AND METHODS The two subject groups in this study were normal controls (n=31) and CAD patients (n=25). The normal contro...

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Skin manifestations in familial heterozygous hypercholesterolemia.

Familial hypercholesterolemia, a form of primary hyperlipoproteinemia, is an autosomal dominant disorder characterized by an increase in serum LDL cholesterol concentrations. Multiple types of xanthomas occur, such as tendinous, tuberous, subperiosteal, and xanthelasma. Intertriginous xanthomas are rare, but if present are pathognomonic in this disorder. We report a patient with multiple xantho...

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Stroke and Cardio-Ankle Vascular Stiffness Index: A Clinical Use

Stroke is the most common cause of neurological disability and impairs quality of life, resulting in early institutionalization. Atherosclerosis is a major contributor to stroke, which can be prevented by early recognition and management. Cardioankle vascular stiffness index (CAVI) was introduced clinically as a novel, simple and non-invasive measure in the assessment of atherosclerosis. CAVI i...

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ژورنال

عنوان ژورنال: Journal of Atherosclerosis and Thrombosis

سال: 2012

ISSN: 1340-3478,1880-3873

DOI: 10.5551/jat.9639